The Effect of Uncertainty in Genotype State on the Inference of Vqtls
نویسندگان
چکیده
##An example using dglm.Pvalues(.) with 200 simulated observations set.seed(123) require(dglm) n = 200 a <rbinom(n, 1, 0.5) ##Covariate for additive genetic effects sex <rbinom(n, 1, 0.5) ##Covariate for a non-genetic effect add.effect = 0 sex.effect = 1 res.var = exp( a*add.effect ) ##Residual variance y <10 + a*add.effect + sex*sex.effect + rnorm(n ,0 , sqrt(res.var)) ##The additive genetic effect must be given first in the following formula d.fit <dglm( formula = y ~ a + sex, dformula = ~ a ) P.values <dglm.Pvalues( d.fit ) print( P.values )
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